When working with Malware infected machines or just poorly performing machines – it is sometimes necessary to clear out temp files. This is where TFC comes in useful. You can pick up this utility here
Described as
TFC (Temp File Cleaner) will clear out all temp folders for all user accounts (temp, IE temp, java, FF, Opera, Chrome, Safari), including Administrator, All Users, LocalService, NetworkService, and any other accounts in the user folder. It also cleans out the %systemroot%temp folder and checks for .tmp files in the %systemdrive% root folder, %systemroot%, and the system32 folder (both 32bit and 64bit on 64bit OSs). It shows the amount removed for each location found (in bytes) and the total removed (in MB). Before running it will stop Explorer and all other running apps. When finished, if a reboot is required the user must reboot to finish clearing any in-use temp files.
TFC only cleans temp folders. TFC will not clean URL history, prefetch, or cookies. Depending on how often someone cleans their temp folders, their system hardware, and how many accounts are present, it can take anywhere from a few seconds to a minute or more. TFC will completely clear all temp files where other temp file cleaners may fail. TFC requires a reboot immediately after running. Be sure to save any unsaved work before running TFC.
So if you need to save some time manually clearing these files or are having some trouble with sticky files give TFC a chance to help.